Author

J. L. Tomasiewicz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Yu· 2 shared S. E. Yang· 2 shared A. B. Spicer· 1 shared B. P. Tu· 1 shared B. R. Miller· 1 shared C. Dantoin· 1 shared C. K. Wille· 1 shared C. L. Green· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

D. Yu

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Author profile →

2 papers

Recent·Most cited

Regulation of metabolic health by dietary histidine in mice

V. Flores, A. B. Spicer, M. Sonsalla, N. E. Richardson, D. Yu, G. E. Sheridan, M. E. Trautman, R. Babygirija, E. P. Cheng, J. M. Rojas, S. E. Yang, M. H. Wakai, R. Hubbell, I. Kasza, J. L. Tomasiewicz, , D. Lamming

This study shows that reducing dietary histidine improves metabolic health and body composition in mice and explains BMI differences in humans.

bioRxiv · Apr 24, 2022Physiology

Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence

S. A. Haws, D. Yu, C. Ye, C. K. Wille, L. C. Nguyen, K. A. Krautkramer, J. L. Tomasiewicz, S. E. Yang, B. R. Miller, W. H. Liu, K. Igarashi, R. Sridharan, B. P. Tu, V. L. Cryns, D. W. Lamming, J. M. Denu

The paper shows that SAM depletion leads to adaptive chromatin changes that maintain heterochromatin stability and epigenetic persistence in mice.

bioRxiv · Sep 12, 2019Biochemistry