Author

J. Lahann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. V. Gregory· 3 shared P. Kadiyala· 3 shared P. R. Lowenstein· 3 shared A. A. Mujeeb· 2 shared A. Comba· 2 shared A. Taher· 2 shared B. L. McClellan· 2 shared K. Banerjee· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioengineering

J. V. Gregory

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Epigenetic reprogramming of autophagy leads to uncovering a novel therapeutic target for mutant IDH1 astrocytomas

F. J. Nunez, K. Banerjee, A. A. Mujeeb, A. Mauser, C. E. Tronrud, Z. Zhu, S. Raghuram, M. R. Sheth, J. A. Pena Agudelo, J. Zelaya, A. Taher, P. Kadiyala, S. V. Carney, M. B. Garcia-Fabiani, A. Comba, , M. Castro

This study identifies autophagy as a critical survival pathway in mIDH1 gliomas and shows that inhibiting autophagy enhances radiosensitivity and tumor regression in preclinical models.

bioRxiv · Mar 8, 2024 · PreprintCancer Biology

Systemic delivery of a CXCR4-CXCL12 signaling inhibitor encapsulated in synthetic protein nanoparticles for glioma immunotherapy

M. S. Alghamri, K. Banerjee, A. A. Mujeeb, A. Taher, R. Thalla, B. L. McClellan, M. L. Varela, S. M. Stamatovic, G. Martinez-Revollar, A. Andjelkovic-Zochowska, J. V. Gregory, P. Kadiyala, A. Calinescu, J. A. Jimenez, A. A. Apfelbaum, , M. G. Castro

This paper develops synthetic protein nanoparticles delivering a CXCR4 inhibitor to treat glioma by enhancing immunotherapy and reducing tumor progression.

bioRxiv · Aug 27, 2021 · PreprintCell Biology

Graph Theoretical Design of Biomimetic Aramid Nanofiber Nanocomposites as Insulation Coatings for Implantable Bioelectronics

N. A. Kotov, H. Zhang, D. Vecchio, A. Emre, S. Rahmani, C. Cheng, J. Zhu, A. Misra, J. Lahann

This paper designs a biomimetic aramid nanofiber nanocomposite insulation material for implantable bioelectronics using graph theory analysis to mimic cartilage structure, showing improved adhesion and biocompatibility compared to Parylene C.

bioRxiv · Dec 28, 2020Bioengineering

Supramolecular Organization Predicts Protein Nanoparticle Delivery to Neutrophils for Acute Lung Inflammation Diagnosis and Treatment

J. W. Myerson, P. N. Patel, N. Habibi, L. R. Walsh, Y.-W. Lee, D. C. Luther, L. T. Ferguson, M. H. Zaleski, M. E. Zamora, O. A. Marcos-Contreras, P. M. Glassman, I. Johnston, E. D. Hood, T. Shuvaeva, J. V. Gregory, , J. S. Brenner

This paper identifies nanoparticle supramolecular organization as a predictor of neutrophil uptake in inflamed lungs, demonstrating diagnostic and therapeutic potential for acute lung inflammation.

bioRxiv · Apr 15, 2020 · PreprintBioengineering

Systemic Brain Tumor Delivery of Synthetic Protein Nanoparticles for Glioblastoma Therapy

J. V. Gregory, P. Kadiyala, R. Doherty, M. Cadena, S. Habeel, E. Ruoslahti, P. R. Lowenstein, M. G. Castro, J. Lahann

This study develops synthetic protein nanoparticles for GBM therapy, showing they deliver STAT3i siRNA to tumors, enhance radiation response, and induce immune memory in mice.

bioRxiv · Jan 9, 2020Bioengineering