O. A. Marcos-Contreras

This study identifies thrombosis as a risk of lung-targeted cationic lipid nanoparticles and proposes solutions to mitigate clotting without compromising targeting.

This paper develops VCAM-targeted lipid nanoparticles to enhance drug delivery to the blood-brain barrier in acute ischemic stroke, reducing infarct volume and mortality.

This paper demonstrates a strategy for targeted drug delivery to the injured brain by loading drugs onto pulmonary leukocytes using ICAM-targeting nanocarriers, showing increased brain uptake and therapeutic effect in a mouse model.

This paper identifies nanoparticle supramolecular organization as a predictor of neutrophil uptake in inflamed lungs, demonstrating diagnostic and therapeutic potential for acute lung inflammation.