Cell BiologybioRxiv
Nonsense Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells with SF3B1 and U2AF1 Mutations
Z. You, A. Cheruiyot, S. Li…·M. J. Walter
This study identifies NMD as a vulnerability in cancer cells with SF3B1 and U2AF1 mutations, showing increased sensitivity to NMD inhibition and potential therapeutic targeting.
DOI 10.1158/0008-5472.can-20-4016