Z. You

Chromosome-level genome assembly of autotetraploid Selenicereus megalanthus and gaining genomic insights into the evolution of trait patterning in diploid and polyploid pitaya species

14-3-3ζ regulates adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation

This study shows 14-3-3ζ regulates adipogenesis by modulating chromatin accessibility in adipose precursor cells, impacting gene expression and fat mass.

The Use of a SOX10 Reporter Towards Ameliorating Oligodendrocyte Lineage Differentiation from Human Induced Pluripotent Stem Cells

The paper develops a SOX10 reporter system to improve the differentiation of oligodendrocytes from iPSCs, enhancing reproducibility and maturity.

SCFFBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation.

The paper identifies FBXW11 as a ubiquitin ligase that targets IL-17RA for proteasomal degradation through lysine 27-linked polyubiquitin chains.

The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery

This study identifies the ATM-E6AP-MASTL axis as a timer-like mechanism that ensures the transient DNA damage checkpoint by promoting cell cycle recovery.

Highly synchronized cortical circuit dynamics mediate spontaneous pain

This study shows that spontaneous pain induces synchronized neural dynamics in the primary somatosensory cortex, and reversing this synchronization alleviates pain.

Nonsense Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells with SF3B1 and U2AF1 Mutations

This study identifies NMD as a vulnerability in cancer cells with SF3B1 and U2AF1 mutations, showing increased sensitivity to NMD inhibition and potential therapeutic targeting.

Multiple expression assessments of ACE2 and TMPRSS2 SARS-CoV-2 entry molecules in the urinary tract and their associations with clinical manifestations of COVID-19