J. M. Hernandez

This paper shows 5-FU's lethality in tumors is due to an RNA damage response, not DNA damage, and that targeting this response could improve cancer therapy.

This study creates a multi-scale, multiomic atlas of human normal and follicular lymphoma lymph nodes to identify tumor-specific features and microenvironmental patterns associated with early relapse.

The paper analyzes the fecal microbiome of children with norovirus gastroenteritis, finding associations between certain bacteria and viral infections.

IBEX enables high-resolution, multi-plex imaging of over 65 parameters in tissue sections without degradation, supporting spatial analysis and integration with other technologies.

This study constructs a single-cell atlas of liver cancer tumor clonality using machine learning and identifies osteopontin as a key driver of tumor evolution and immune reprogramming.