Author

J. N. Francis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

A. R. Smith· 2 shared M. S. Kay· 2 shared A. E. Siglin· 1 shared B. D. Welch· 1 shared C. P. Hill· 1 shared D. M. Eckert· 1 shared E. Jesteadt· 1 shared F. G. Whitby· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

A. R. Smith

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2 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedAug 20, 2020

Prevention and Treatment of SHIVAD8 Infection in Rhesus Macaques by a Potent D-peptide HIV Entry Inhibitor

Y. Nishimura, J. N. Francis, O. Donau…·M. S. Kay

This study demonstrates that CPT31, a D-peptide HIV entry inhibitor, prevents SHIV infection in rhesus macaques and reduces viral load in chronically infected animals.

DOI 10.1073/pnas.2009700117

ratexperimental assay

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MicrobiologybioRxivAug 28, 2019

Characterization of resistance to a potent D-peptide HIV entry inhibitor

A. R. Smith, M. T. Weinstock, A. E. Siglin…·M. S. Kay

This study identifies mutations conferring resistance to the D-peptide HIV inhibitor PIE12-trimer and shows they reduce inhibitor affinity but also impair viral fitness.

DOI 10.1186/s12977-019-0489-7

humanproteomics

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