M. S. Kay

This paper develops a synthetic delivery vector for mucosal vaccination that induces mucosal immunity and CD8+ T cell responses in mice.

This study demonstrates that CPT31, a D-peptide HIV entry inhibitor, prevents SHIV infection in rhesus macaques and reduces viral load in chronically infected animals.

The paper uses fusion inhibitors to trap HIV-1 in a pre-hairpin intermediate state and visualizes it via electron tomography, revealing the structure of Env-mediated fusion.

The paper investigates how diarrheal pathogens drive evolutionary changes in the GC-C receptor and its ligand in mammals, showing evidence of positive selection and coevolution.

This study identifies mutations conferring resistance to the D-peptide HIV inhibitor PIE12-trimer and shows they reduce inhibitor affinity but also impair viral fitness.