Author

J. N. Lakins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

E. S. Hwang· 2 shared V. M. Weaver· 2 shared A. C. Nelson· 1 shared A. Chauhan· 1 shared A. J. Ironside· 1 shared A. Nasir· 1 shared A. P. Drain· 1 shared A. S. Barrett· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

E. S. Hwang

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 19, 2022

Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer progression

J. J. Northey, Y. Yui, M.-K. Hayward…·V. M. Weaver

The paper shows that stiff extracellular matrix and integrin mechanosignaling increase mammary stem-progenitor cells, promoting breast cancer risk and progression through RANK signaling.

DOI 10.1101/2022.04.19.487741

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivFeb 13, 2020

Inflammation promotes tumor aggression by stimulating stromal cell-dependent collagen crosslinking and stromal stiffening

O. Maller, A. P. Drain, A. S. Barrett…·V. M. Weaver

This study shows that inflammation promotes tumor aggression by stimulating stromal cell-dependent collagen crosslinking and stiffening, identifying lysyl hydroxylase two as a biomarker.

DOI 10.1038/s41563-020-00849-5

humanproteomics

𝕏 PostBluesky