Author

O. Maller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

A. C. Nelson· 1 shared A. Chauhan· 1 shared A. Combes· 1 shared A. Nasir· 1 shared A. P. Drain· 1 shared A. S. Barrett· 1 shared B. Ruffell· 1 shared B. Samad· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. C. Nelson

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2 papers

Recent·Most cited

Myeloid mechano-metabolic programming restricts anti-tumor immunity

K. Tharp, K. Kersten, O. Maller, G. Timblin, C. Stashko, F. Canale, M.-K. Hayward, I. Berestjuk, J. ten Hoeve-Scott, B. Samad, R. Geiger, A. Combes, V. Weaver

This study shows that fibrotic tumor microenvironments impair anti-tumor immunity through myeloid cell-driven metabolic changes that hinder CD8+ T cell function.

bioRxiv · Jul 14, 2022 · PreprintCancer Biology

Inflammation promotes tumor aggression by stimulating stromal cell-dependent collagen crosslinking and stromal stiffening

O. Maller, A. P. Drain, A. S. Barrett, S. Borgquist, B. Ruffell, P. T. Thanh, T. Gruosso, H. Kuasne, J. N. Lakins, I. Acerbi, J. M. Barnes, T. Nemkov, A. Chauhan, J. Gruenberg, A. Nasir, , V. M. Weaver

This study shows that inflammation promotes tumor aggression by stimulating stromal cell-dependent collagen crosslinking and stiffening, identifying lysyl hydroxylase two as a biomarker.

bioRxiv · Feb 13, 2020Cancer Biology