Cancer BiologybioRxivPreprint
Myeloid mechano-metabolic programming restricts anti-tumor immunity
K. Tharp, K. Kersten, O. Maller…·V. Weaver
This study shows that fibrotic tumor microenvironments impair anti-tumor immunity through myeloid cell-driven metabolic changes that hinder CD8+ T cell function.
DOI 10.1101/2022.07.14.499764