Author

J. Nideffer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A.-M. Cepika· 1 shared B. C. Thomas· 1 shared B. Greenhouse· 1 shared B. Pulendran· 1 shared C. Waichler· 1 shared F. Mueller· 1 shared F. Nankya· 1 shared G. Dorsey· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A.-M. Cepika

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells

A.-M. Cepika, L. Amaya, C. Waichler, M. Narula, M. M. Mantilla, B. C. Thomas, P. P. Chen, R. A. Freeborn, M. Pavel-Dinu, J. Nideffer, M. Porteus, R. Bacchetta, F. Mueller, W. J. Greenleaf, H. Y. Chang, M. G. Roncarolo

This study identifies the epigenetic signature and key transcription factors regulating human antigen-specific Tr1 cells, revealing their unique biology and potential for therapeutic applications.

bioRxiv · Mar 7, 2024 · PreprintImmunology

Disease Tolerance Acquired Through Repeated Plasmodium Infection Involves Epigenetic Reprogramming of Innate Immune Cells

J. Nideffer, M. Ty, M. Donato, J. Rek, R. Kajubi, X. Ji, H. Maecker, F. Nankya, K. Musinguzi, K. Press, B. Greenhouse, M. Kamya, M. E. Feeney, G. Dorsey, P. Utz, , P. Jagannathan

The paper shows that repeated Plasmodium infection leads to epigenetic changes in innate immune cells, which suppress inflammation and confer long-term disease tolerance in Ugandan children.

bioRxiv · Apr 19, 2023 · PreprintImmunology