J. P. Higham

This paper identifies GPR35 as a target for non-opioid analgesics by showing it inhibits TRPA1-mediated colonic hypersensitivity through suppression of Substance P release.

This study examines how early life adversity affects survival in male and female rhesus macaques, finding sex-dependent differences in mortality risk across the lifespan.

This paper reviews how social adversity affects aging in rhesus macaques, focusing on ecological and social factors and the impact of Hurricane Maria.

This study examines how social relationships affect parasitic infection risk in rhesus macaques, finding that affiliative partners reduce protozoa infection risk, while social status does not.

This paper develops an epigenetic clock for rhesus macaques using DNA methylation data, achieving high accuracy in predicting age across different populations and species.

This study shows IL-13 sensitizes colonic nociceptors via JAK and p38 MAPK signaling, offering therapeutic targets for visceral pain in gastrointestinal diseases.

This study examines how ageing affects social network structure in rhesus macaques using empirical data and an agent-based model, finding age-related changes in indirect connectivity but no overall network structure age distribution relationship.

This study shows that older female rhesus macaques reduce their social networks and prioritize previously beneficial partners, indicating social selectivity with age.

The paper investigates how sociality affects injury risk and survival in rhesus macaques, finding that social integration reduces injury risk but not mortality after injury.

This study examines how age, sex, and social status affect immune cell composition in rhesus macaques, revealing age-related immunosenescence and sex-dependent effects of social adversity.

This study compares sex-biased gene expression in human and rhesus macaque brains across 16 regions, finding limited overlap and greater sexual dimorphism in humans.

The paper uses machine learning to identify key facial traits for species discrimination in guenons and validates these findings with behavioral experiments.

This study shows female rhesus macaques spend more time looking at more masculine male faces in controlled experiments, suggesting they can perceive facial masculinity.