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J. R. Doerr

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Bhattacharya· 1 shared A. Eggert· 1 shared A. Heeren-Hagemann· 1 shared A. Henssen· 1 shared C. Schmitt· 1 shared E. Rodriguez-fos· 1 shared H. Dorado Garcia· 1 shared J. Kirwan· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperCancer Biology

A. Bhattacharya

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 8, 2022

Amplicon structure creates collateral therapeutic vulnerability in cancer

Y. Bei, L. Brame, M. Kirchner…·A. Henssen

The paper identifies DDX1 as a passenger gene co-amplified with MYCN in cancer, showing that its aberrant expression creates a therapeutic vulnerability through mTORC1 dependency.

DOI 10.1101/2022.09.08.506647

humanDNA methylation

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