MicrobiologybioRxiv
The multi-functional reovirus σ3 protein is a virulence factor that suppresses stress granule formation to allow viral replication and myocardial injury
Y. Guo, M. M. Hinchman, M. Lewandrowski…·J. S. L. Parker
This study identifies σ3 as a reovirus virulence factor that suppresses PKR activation and stress granule formation, linking these functions to viral replication and myocardial injury in mice.
DOI 10.1371/journal.ppat.1009494