Cell BiologybioRxivPreprint
Polyubiquitinated PCNA promotes alternative lengthening of telomeres by inducing break-induced replication
S. Kim, N. Kang, J. S. Ra…·K.-y. Lee
The paper shows polyubiquitinated PCNA promotes break-induced replication at telomeres and fragile sites by recruiting SLX4, leading to telomere damage and DNA synthesis.
DOI 10.1101/2023.07.13.548953