Cancer BiologybioRxivPreprint
Targeting Scavenger Receptor Type B1 In Cholesterol-Addicted Lymphomas Abolishes Glutathione Peroxidase 4 and Results in Ferroptosis
J. S. Rink, A. Lin, K. M. McMahon…·L. I. Gordon
This study shows that targeting SCARB1 with HDL NPs in cholesterol-dependent lymphoma cells reduces GPX4, leading to ferroptosis and cell death.