Author

J. Singla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Li· 1 shared A. Sali· 1 shared B. Raveh· 1 shared C. Kesselman· 1 shared C. Wang· 1 shared D. Zheng· 1 shared J. Tempkin· 1 shared J. Zha· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Li

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2 papers

Recent·Most cited

Enhancing affinity of neutralizing SARS-CoV-2 nanobody through facile structure-guided mutations in CDRs

V. Singh, M. Bhutkar, S. Choudhary, S. Nehul, R. Kumar, J. Singla, P. Kumar, S. Tomar

This study enhances the affinity of SARS-CoV-2 neutralizing nanobodies through structure-guided mutations in CDRs, resulting in improved neutralization activity against pseudovirus.

bioRxiv · May 13, 2024 · PreprintBioengineering

Bayesian metamodeling of complex biological systems across varying representations

B. Raveh, L. Sun, K. L. White, T. Sanyal, J. Tempkin, D. Zheng, K. Bharath Pilla, J. Singla, C. Wang, J. Zha, A. Li, N. A. Graham, C. Kesselman, R. C. Stevens, A. Sali

This paper introduces Bayesian metamodeling to integrate diverse models of biological systems, demonstrating its application to glucose-stimulated insulin secretion in pancreatic β-cells.

bioRxiv · Mar 29, 2021Cell Biology