Author

J. Stokes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

J. Snell· 2 shared K. Y. Park· 2 shared M. M. Sedensky· 2 shared P. G. Morgan· 2 shared R. Bornstein· 2 shared S. C. Johnson· 2 shared A. Freed· 1 shared A. Pan· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersPathology

J. Snell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Leukocyte proliferation mediates disease pathogenesis in the Ndufs4(KO) mouse model of Leigh syndrome

J. Stokes, R. Bornstein, K. James, K. Y. Park, K. Spencer, K. Vo, J. Snell, B. M. Johnson, P. G. Morgan, M. M. Sedensky, P. G. Morgan, N. A. Baertsch, S. C. Johnson

The paper shows that leukocyte proliferation drives Leigh syndrome pathology in Ndufs4(KO) mice, and leukocyte depletion prevents CNS lesions and extends survival.

bioRxiv · Nov 11, 2021 · PreprintPathology

Mechanisms underlying neonate specific metabolic effects of volatile anesthetics

J. Stokes, A. Freed, A. Pan, G. X. Sun, R. Bornstein, J. Snell, K. Y. Park, P. G. Morgan, M. M. Sedensky, S. C. Johnson

This study identifies a neonate-specific metabolic effect of volatile anesthetics, showing they deplete beta-hydroxybutarate at sub-anesthetic concentrations, mediated by citrate and malonyl-CoA changes, which adults are less sensitive to.

bioRxiv · Dec 8, 2020Physiology

The biofilm matrix scaffold of Pseudomonas species contains non-canonically base paired extracellular DNA and RNA

T. W. Seviour, F. R. Winnerdy, W. Lan Li, S. Xiangyan, S. Mugunthan, R. Castaig, S. S. Adav, G. S. Kohli, H. M. Shewan, J. Stokes, S. A. Rice, A.-T. Phan, S. Kjelleberg

This study isolates extracellular DNA from Pseudomonas biofilms and identifies non-canonical base pairs and RNA interactions that contribute to the viscoelastic properties of the biofilm matrix.

bioRxiv · May 29, 2020 · PreprintBiochemistry