A. Perry

Evaluating genomic offset predictions in a forest tree with high population genetic structure

This study evaluates genomic offset predictions in maritime pine using multiple methods and data sources, finding strong associations with mortality but not height.

Epigenetic reprogramming shapes the cellular landscape of schwannoma

This study identifies two molecular groups in schwannomas driven by epigenetic reprogramming and shows ionizing radiation can reprogram neural crest to immune-enriched schwannomas.

Evaluation of the fitness benefit conferred by RNA cis-regulators to Streptococcus pneumoniae during infection

This study evaluates the fitness benefit of RNA cis-regulators in Streptococcus pneumoniae during infection, finding that mis-regulation significantly reduces fitness in vivo.

NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy

This study identifies NOTCH3 as a driver of meningioma tumorigenesis and radiotherapy resistance, showing its role in tumor growth and survival in preclinical models.

Characterisation of key genotypic and phenotypic traits of clinical cystic fibrosis Staphylococcus aureus isolates

This study characterizes the genotypic and phenotypic traits of 25 clinical Staphylococcus aureus isolates from cystic fibrosis patients, revealing genetic and phenotypic variation and antimicrobial resistance patterns.

Phenotypic trait variation in a long-term, multisite common garden of Scots pine in Scotland

The paper describes a long-term common garden experiment of Scots pine to study phenotypic trait variation across environments and its genetic basis.

Escaping the Fate of Sisyphus: Assessing Resistome Hybridization Baits for Antimicrobial Resistance Gene Capture

The paper evaluates hybridization capture baits for antimicrobial resistance gene detection, showing their effectiveness and providing guidelines for updating bait sets as new resistance genes are discovered.

Larvae and adults exhibit contrasting patterns of immune gene expression and infection resistance in wild flour beetle populations

This study compares immune gene expression and infection resistance between larvae and adults in two flour beetle species across lab and wild populations, finding higher adult investment and resistance.

Identifying and testing marker-trait associations for growth and phenology in three pine species: implications for genomic prediction

This study identifies SNP-trait associations in three pine species and evaluates genomic prediction models for growth and phenology traits in field trials.

A subset of pediatric thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR

This study identifies a distinct subset of pediatric gliomas with EGFR alterations, H3K27me3 loss, and broad tumor localization, suggesting EGFR inhibition as a potential therapy.

Natural variation in the contribution of microbial density to inducible immune dynamics

This study examines natural variation in inducible immune responses in flour beetles by analyzing AMP gene expression during infection with different bacteria, showing density-dependent and independent dynamics.

GNI-A1 mediates trade-off between grain number and grain weight in tetraploid wheat

This study identifies GNI-A1 as a gene mediating the trade-off between grain number and grain weight in tetraploid wheat through fine-mapping and functional analysis.