Author

J. Trebicka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

R. Schierwagen· 2 shared A. Fullam· 1 shared A. Krag· 1 shared A. Odainic· 1 shared A. Roers· 1 shared A. Zibert· 1 shared B. Steglich· 1 shared C. Broens· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

R. Schierwagen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations

S. Nishijima, E. Stankevic, O. Aasmets, T. S. Schmidt, N. Nagata, M. I. Keller, P. Ferretti, H. Juel, A. Fullam, C. Schudoma, S. M. Robbani, J. K. Hansen, L. A. Holm, M. Israelsen, R. Schierwagen, , P. Bork

This study shows that fecal microbial load, not disease, is the main driver of gut microbiome changes and identifies it as a major confounder in microbiome studies.

bioRxiv · Mar 18, 2024Microbiology

Molecular determinants of SEC61A1 mutant R236C in two patient-derived cellular platforms

M. Weiand, V. Sandfort, O. Nadzemova, R. Schierwagen, J. Trebicka, I. Kabar, H. Schmidt, A. Zibert

The paper assesses the molecular phenotype of SEC61A1 R236C mutation in two patient-derived cellular models, finding reduced autophagy, cAMP synthesis, and increased calcium leakiness, with similar overall effects across cell types.

bioRxiv · Dec 5, 2023 · PreprintCell Biology

Suppression of systemic T cell immunity to viral infection during liver injury is prevented by inhibition of interferon and IL-10 signaling

P. C. Hackstein, J. Spitzer, K. Symeonidis, H. Horvatic, T. Bedke, B. Steglich, L. Assmus, A. Odainic, N. Kessler, S. Klein, M. Beyer, R. Schmithausen, E. Latz, C. Kurts, J. Trebicka, , Z. Abdullah

The paper shows that liver injury suppresses systemic T cell immunity to viral infection, which can be reversed by inhibiting interferon and IL-10 signaling in preclinical models and human patients.

bioRxiv · Jul 21, 2022 · PreprintImmunology