Author

J. Welch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Benabdelmouna· 1 shared A. Chi· 1 shared A. Dow· 1 shared A. Simon· 1 shared A. Taher· 1 shared A. Villalba· 1 shared C. Arbiol· 1 shared C. Gao· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperEvolutionary Biology

A. Benabdelmouna

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inactivation of Highly Transmissible Livestock and Avian Viruses Including Influenza A and Newcastle Disease Virus for Molecular Diagnostics

J. Welch, R. Shrestha, H. Hutchings, N. Pal, R. Levings, S. Robbe-Austerman, R. Palinski, K. Shanmuganatham

This study shows that PrimeStore(R) molecular transport media inactivates viruses by >99.99% without affecting nucleic acid detection, enabling safer and more efficient diagnostic testing.

bioRxiv · Sep 13, 2023 · PreprintMicrobiology

Prevalence and polymorphism of a mussel transmissible cancer in Europe

M. Hammel, A. Simon, C. Arbiol, A. Villalba, E. A. V. Burioli, J.-F. Pepin, J.-B. Lamy, A. Benabdelmouna, I. Bernard, M. Houssin, G. M. Charriere, D. Destoumieux-Garzon, J. Welch, M. J. Metzger, N. Bierne

The paper screens European mussels for transmissible cancer lineages, finding low prevalence of MtrBTN2 and polymorphism suggesting complex diversification.

bioRxiv · Mar 31, 2021Evolutionary Biology

Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling

X. Li, D. Chandra, S. Letarte, G. Adam, J. Welch, R.-S. Yang, S. Bodea, A. Dow, A. Chi, C. Strulson, D. Richardson

This study uses activity-based protein profiling to identify active enzymes causing polysorbate degradation in biotherapeutic production, finding more enzymes than traditional proteomics methods.

bioRxiv · Oct 7, 2020Bioengineering

G-CSF SECRETED BY EPIGENETICALLY REPROGRAMMED MUTANT IDH1 GLIOMA STEM CELLS REVERSES THE MYELOID CELLS'-MEDIATED IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT

M. S. Alghamri, R. Avvari, R. Thalla, N. Kamran, L. Zhang, M. Ventosa, A. Taher, S. Faisal, F. Nunez, M. Garcia-Fabiani, S. Haase, S. Carney, D. Orringer, S. Hervey-Jumper, J. Heth, , M. G. Castro

The paper shows that mIDH1 glioma stem cells secrete G-CSF, which reprograms myeloid cells to become non-immunosuppressive, altering the tumor microenvironment.

bioRxiv · Jul 22, 2020 · PreprintCancer Biology