Author

D. Chandra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Aggarwal· 1 shared A. Akerman· 1 shared A. Beck· 1 shared A. Chi· 1 shared A. D. Kelleher· 1 shared A. Dow· 1 shared A. Jahangir· 1 shared A. Khromykh· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Aggarwal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2

A. Aggarwal, C. Fichter, V. Milogiannakis, T. Ison, M. Ruiz Silva, C. Esneau, N. Bartlett, L. Burrell, S. Patel, M. Churchill, T. Angelovich, R. Parry, J. D. Sng, G. G. Neely, C. L. Moreno, , S. G. Turville

The paper shows Omicron SARS-CoV-2 lineages rely on ACE2 without TMPRSS2 complexes for entry, due to changes in the ACE2 Collectrin-Like Domain affecting TMPRSS2 activation.

bioRxiv · Sep 22, 2023 · PreprintMicrobiology

Global transcriptome analysis reveals Salmonella Typhimurium employs the nitrate-dependent anaerobic pathway to combat bile stress

M. Singh, D. Chandra, S. Jagdish, D. Nandi

This study identifies nitrate-dependent anaerobic metabolism as a key mechanism for Salmonella Typhimurium to survive bile stress through transcriptome analysis.

bioRxiv · Jun 15, 2023 · PreprintMicrobiology

Tumor-targeted delivery of childhood vaccine recall antigens by attenuated Listeria reduces pancreatic cancer

B. C. Selvanesan, D. Chandra, W. Quispe-Tintaya, A. Jahangir, A. Patel, K. Meena, R. Alberto Alves Da Silva, M. Friedman, J. Li, S. Siddiqui, S. K. Libutti, Z. Yuan, A. Beck, L. Tesfa, W. Koba, , C. Gravekamp

This study shows that delivering a childhood vaccine antigen via attenuated Listeria improves immunotherapy for pancreatic cancer by converting cold tumors into hot tumors and enhancing T cell activity.

bioRxiv · Jun 4, 2021 · PreprintImmunology

Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling

X. Li, D. Chandra, S. Letarte, G. Adam, J. Welch, R.-S. Yang, S. Bodea, A. Dow, A. Chi, C. Strulson, D. Richardson

This study uses activity-based protein profiling to identify active enzymes causing polysorbate degradation in biotherapeutic production, finding more enzymes than traditional proteomics methods.

bioRxiv · Oct 7, 2020Bioengineering