Author

J. Whitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

E. M. Eshleman· 2 shared L. Engleman· 2 shared T. Alenghat· 2 shared T. Rice· 2 shared V. Woo· 2 shared A. M. Carter· 1 shared B. A. Vallance· 1 shared H. Chen· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

E. M. Eshleman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Intestinal epithelial MHC class II regulation by HDAC3 instructs microbiota-specific CD4+ T cells

E. M. Eshleman, T.-Y. Shao, V. Woo, T. Rice, J. Whitt, L. Engleman, S. S. Way, T. Alenghat

This study shows that epithelial HDAC3 regulates MHCII expression, which limits commensal-specific Th17 cells and prevents microbiota-triggered inflammation.

bioRxiv · Jan 1, 2022Immunology

Commensal bacterial-derived retinoic acid primes host defense to intestinal infection

T. Alenghat, V. Woo, E. M. Eshleman, J. Whitt, S. Hashimoto-Hill, S.-e. Wu, L. Engleman, T. Rice, R. Karns, B. A. Vallance

This study identifies retinoic acid (RA) as a microbiota-derived metabolite that enhances intestinal defense against infection by modulating host gene expression.

bioRxiv · Jan 27, 2021Microbiology

Novel anti-somatostatin receptor 2 antibody-drug conjugate for neuroendocrine cancer therapy

Y. Si, S. Kim, R. Guenter, J. Ou, Y. Lu, K. Chen, J. Zhang, J. Whitt, A. M. Carter, J. A. Bibb, J. M. Markert, R. Jaskula-Sztul, L. Zhou, H. Chen, X. Liu

This study develops an anti-somatostatin receptor 2 antibody-drug conjugate (ADC) that effectively targets and kills neuroendocrine tumors with minimal toxicity.

bioRxiv · Nov 18, 2019 · PreprintBioengineering