Nature of active forces in tissues: how contractile cells can form extensile monolayers
L. Balasubramaniam, A. Doostmohammadi, T. B. Saw, G. Sankara, R. Mueller, T. Dang, M. Thomas, S. Gupta, S. Sonam, A. S. Yap, Y. Toyama, R.-M. Mege, J. Yeomans, B. Ladoux
The paper investigates how epithelial cell monolayers switch from extensile to contractile behavior as intercellular contacts weaken, revealing mechanotransductive responses and implications for cell sorting and tissue dynamics.
bioRxiv · Oct 28, 2020Biophysics