ImmunologybioRxivPreprint
Step-wise epigenetic signal integration governs adaptive programming of cytotoxic lymphocytes
S. Grassmann, E. K. Santosa, H. Kim…·J. C. Sun
This study shows that interleukin-12 signaling integrates with antigen receptor signals in a context-dependent manner to determine the epigenetic and functional fate of cytotoxic lymphocytes.