Author

S. Grassmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Biochemistry· 1

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Research Focus:cell type annotation· 4 Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. C. Sun· 4 shared H. Kim· 2 shared A. C. Stiel· 1 shared A. M. Mujal· 1 shared A. Straub· 1 shared C. M. Lau· 1 shared D. Busch· 1 shared D. Wethington· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersImmunology

J. C. Sun

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Author profile →

5 papers

Recent·Most cited

IL-21 Shapes the B Cell Response in a Context-Dependent Manner

Y. Kim, F. Manara, S. Grassmann, K. Belcheva, K. Reyes, H. Kim, S. Downs-Canner, W. T. Yewdell, J. C. Sun, J. Chaudhuri

This study reveals that IL-21 regulates B cell fate through context-dependent effects on apoptosis and proliferation, using a conditional knock-out model and ex vivo cultures.

bioRxiv · Jul 13, 2024Immunology

Step-wise epigenetic signal integration governs adaptive programming of cytotoxic lymphocytes

S. Grassmann, E. K. Santosa, H. Kim, I. B. Johnson, A. M. Mujal, J.-B. LeLuduec, S. X. Fan, M. Owyong, A. Straub, L. Deng, C. M. Lau, K. Hsu, D. Busch, J. C. Sun

This study shows that interleukin-12 signaling integrates with antigen receptor signals in a context-dependent manner to determine the epigenetic and functional fate of cytotoxic lymphocytes.

bioRxiv · Nov 7, 2023 · PreprintImmunology

Single-Cell Profiling Reveals a Naive-Memory Relationship between CD56bright and Adaptive Human Natural Killer Cells

M. K. Panjwani, S. Grassmann, R. Sottile, J.-B. Le Ludeuc, T. Kontopoulos, K. van der Ploeg, J. C. Sun, K. C. Hsu

The paper identifies a naive-memory relationship between CD56bright and adaptive human natural killer cells through phenotypic, transcriptional, and functional profiling.

bioRxiv · Sep 23, 2023 · PreprintImmunology

Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative ability

D. Wethington, S. Ahmad, M. Potempa, G. Giuliani, O. A. Aguilar, M. Poudel, S. Grassmann, W. Stewart, N. M. Adams, J. C. Sun, L. L. Lanier, J. Das

This study quantifies how clonal stochasticity in NK cell responses to MCMV arises from proliferation and death dynamics of mature NK subsets.

bioRxiv · Sep 7, 2023Immunology

Multiplexed whole animal imaging with reversibly switchable optoacoustic proteins

K. Mishra, M. Stankevych, J. P. Fuenzalida-Werner, S. Grassmann, V. Gujrati, U. Klemm, V. R. Buchholz, V. Ntziachristos, A. C. Stiel

The paper introduces two photochromic proteins for multiplexed in vivo optoacoustic imaging and develops software to enable temporal signal unmixing in commercial systems.

bioRxiv · Feb 1, 2020Biochemistry