NeurosciencebioRxivPreprint
Reduced S-acylation of SQSTM1/p62 in Huntington disease is associated with impaired autophagy
Fatima Abrar, Martyn C. Davies, A. Kumar…·Dale D. O. Martin
The paper shows reduced S-acylation of SQSTM1/p62 in Huntington disease impairs autophagy by blocking autophagic flux and causing empty autophagosomes.