Author

K. A. Mapuskar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. R. Jackson· 1 shared A. Rauckhorst· 1 shared A. Simoni· 1 shared B. G. Allen· 1 shared C. D. Heer· 1 shared D. R. Spitz· 1 shared D. Zepeda-Orozco· 1 shared E. B. Taylor· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. R. Jackson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury

A. Rauckhorst, G. V. Martinez, G. M. Andrade, H. Wen, J. Y. Kim, A. Simoni, K. A. Mapuskar, P. Rastogi, E. J. Steinbach, M. L. McCormick, B. G. Allen, A. R. Jackson, N. S. Pabla, M. C. Coleman, D. R. Spitz, , D. Zepeda-Orozco

The paper shows that reducing mitochondrial pyruvate carrier activity in kidney tubular cells protects against acute kidney injury by enhancing redox defenses and survival.

bioRxiv · Jan 31, 2023Biochemistry

Succinate accumulation links mitochondrial MnSOD depletion to aberrant nuclear DNA methylation and altered cell fate

K. L. Cramer-Morales, C. D. Heer, K. A. Mapuskar, F. E. Domann

This study shows that MnSOD loss in human erythroleukemia cells leads to succinate accumulation, reduced TET activity, and impaired erythroid differentiation.

bioRxiv · Jun 24, 2020 · PreprintCancer Biology