K. Braunger

Targeting properdin - Structure and function of a novel family of tick-derived complement inhibitors

This study identifies and characterizes a novel family of tick-derived complement inhibitors, CirpA, which bind to properdin and inhibit complement activation.

Structural and mutational analysis of the ribosome-arresting human XBP1u

This study presents a cryo-EM structure of XBP1u and shows that only specific mutations in its AP region are optimal for translational arrest.