ImmunologybioRxiv
A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans
S. S. Gang, M. Grover, K. C. Reddy…·E. R. Troemel
This paper identifies a PALS-25 gain-of-function mutant in C. elegans that activates immune responses against both epidermal and intestinal pathogens through cross-tissue signaling.
DOI 10.1371/journal.pgen.1010314