Author

K. Crasta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. B. Maier· 1 shared A. D. Jeyasekharan· 1 shared A. Eisenmenger· 1 shared A. Shendre· 1 shared B. W. Q. Tan· 1 shared C. Frezza· 1 shared D. Kappei· 1 shared D. S. P. Tan· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. B. Maier

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Author profile →

2 papers

Recent·Most cited

Therapeutic effect of dietary interventions on senescence in animals and humans: A systematic review

L. Guan, A. Eisenmenger, K. Crasta, E. Sandalova, A. B. Maier

This review evaluates dietary interventions for reducing cellular senescence in animals and humans, finding resveratrol, vitamin E, and soy protein isolate show promise in animal studies, but human evidence is limited.

bioRxiv · Jul 28, 2023Cell Biology

PLK1 inhibition selectively kills ARID1A deficient cells through uncoupling of oxygen consumption from ATP production

U. S. Srinivas, G. K. Ramachandran, J. D. Wardyn, M. M. Hoppe, Y. Peng, S. Lim, M. Y. Lee, P. C. Peethala, O. An, A. Shendre, B. W. Q. Tan, T. S. C. Norbert, P. Jaynes, L. Hu, R. Jakhar, , A. D. Jeyasekharan

This study identifies ARID1A deficiency as a biomarker for PLK1 inhibitor sensitivity by revealing a mitochondrial metabolic vulnerability in these cells.

bioRxiv · Jun 1, 2021 · PreprintCancer Biology