Author

K. Cunningham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Dansik· 1 shared A. Kusoglu· 1 shared A. Mukundan· 1 shared A. P. Hinck· 1 shared A. Sanders· 1 shared C. Ciancia· 1 shared C. S. Hinck· 1 shared C. Schoenherr· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

A. Dansik

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The helminth TGF-beta mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-beta receptors to preferentially target myeloid cells

S. Singh, D. J. Smyth, K. Cunningham, A. Mukundan, C.-H. Byron, C. S. Hinck, M. P. J. White, C. Ciancia, N. Wosowska, A. Sanders, R. Jin, S. Lilla, S. Zanivan, C. Schoenherr, G. Inman, , R. M. Maizels

This paper identifies TGM4, a helminth TGF-beta mimic, as a modular ligand that selectively targets myeloid cells through specific receptor interactions, differing from TGM1's broader T cell targeting.

bioRxiv · Nov 13, 2023 · PreprintImmunology

Extracellular matrix sulfation in the tumor microenvironment stimulates cancer stemness and invasiveness

A. Kusoglu, D. Ornek, A. Dansik, C. Uzun, S. N. Ozkan, S. Sarica, K. Yangin, S. Ozdinc, D. Turan Sorhun, N. Solcan, E. C. Doganalp, O. Arlov, K. Cunningham, I. C. Karaoglu, S. Kizilel, , E. Ozturk

The paper shows that increased sulfation in tumor ECM promotes cancer stemness and invasiveness through FAK-PI3K-mTOR signaling and RTK activation.

bioRxiv · Oct 17, 2023Bioengineering

Adaptive structural and functional evolution of the placenta protects fetal growth in high elevation deer mice

K. Wilsterman, E. C. Moore, R. M. Schweizer, K. Cunningham, J. M. Good, Z. A. Cheviron

This study investigates how high elevation adaptation in deer mice affects placental structure and function to protect fetal growth under hypoxia, identifying conserved genetic pathways and genomic features involved.

bioRxiv · Sep 27, 2022Evolutionary Biology