Author

K. D. Sutherland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. Batrouney· 1 shared A. Kersbergen· 1 shared A. L. Garnham· 1 shared A. M. Olthof· 1 shared B. B. Williams· 1 shared C. Khoo· 1 shared J. Coates· 1 shared J. K. Heath· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Batrouney

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Author profile →

2 papers

Recent·Most cited

Brief report: Reclassifying SCLC-Y as SMARCA4 deficient malignancies - resolving the controversy

J. Ng, L. Cai, L. Girard, O. Prall, N. Rajan, C. Khoo, A. Batrouney, A. Kersbergen, M. Christie, J. Minna, M. L. Burr, K. D. Sutherland

The paper reclassifies YAP1-expressing SCLC-Y as SMARCA4-deficient malignancies, showing they lack SCLC features and instead resemble SMARCA4-deficient tumors.

bioRxiv · Oct 9, 2022Cancer Biology

The minor spliceosome offers a therapeutically viable target for the treatment of a broad spectrum of cancers

K. Doggett, K. J. Morgan, S. Mieruszynski, B. B. Williams, A. M. Olthof, A. L. Garnham, M. J. G. Milevskiy, L. Whitehead, J. Coates, M. Buchert, R. J. O'Donoghue, T. E. Hall, Z. Gong, T. L. Putoczki, M. Ernst, , J. K. Heath

This study shows that targeting the minor spliceosome, specifically Rnpc3, reduces tumor burden in multiple cancer models and is associated with poor patient survival in cancer transcriptomes.

bioRxiv · Dec 9, 2021Cancer Biology