Temperature elevation synergises with and enhances the type-I IFN-mediated restriction of MPXV
C. Davis, I. Epifano, K. Dee, S. McFarlane, J. K. Wojtus, B. Brennan, Q. Gu, S. B. Vattipally, L. Tong, L. Orr, A. D. S. Filipe, D. A. Barr, A. Ho, E. C. Thomson, C. Boutell
This study shows that fever enhances the host's type-I IFN response to restrict MPXV replication.
bioRxiv · Sep 29, 2023 · PreprintMicrobiology