MicrobiologybioRxiv
Editing of the TRIM5 gene decreases the permissiveness of human T lymphocytic cells to HIV-1
K. Desaulniers, L. Ortiz, C. Dufour…·L. Berthoux
This study edits the TRIM5 gene in human T cells to restrict HIV-1 infection, showing biallelic modification is needed for significant inhibition.
DOI 10.3390/v13010024