Author

C. Dufour

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

L. Berthoux· 3 shared M. B. Plourde· 3 shared N. Merindol· 3 shared A. Claudel· 2 shared A. Pagliuzza· 1 shared C. Sacdalan· 1 shared D. Hsu· 1 shared E. Kroon· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

L. Berthoux

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HIV rapidly targets a diverse pool of CD4+ T cells to establish productive and latent infections

P. Gantner, S. Buranapraditkun, A. Pagliuzza, C. Dufour, M. Pardons, J. L. Mitchell, E. Kroon, C. Sacdalan, N. Tulmethakaan, S. Pinyakorn, M. L. Robb, N. Phanuphak, J. Ananworanich, D. Hsu, S. Vasan, , N. Chomont

This study identifies that HIV initially infects diverse CD4+ T cells in blood and lymph nodes, establishing both productive infections and latent reservoirs simultaneously.

bioRxiv · May 10, 2022Microbiology

Editing of the TRIM5 gene decreases the permissiveness of human T lymphocytic cells to HIV-1

K. Desaulniers, L. Ortiz, C. Dufour, A. Claudel, M. B. Plourde, N. Merindol, L. Berthoux

This study edits the TRIM5 gene in human T cells to restrict HIV-1 infection, showing biallelic modification is needed for significant inhibition.

bioRxiv · Dec 7, 2020Microbiology

Editing of the Human TRIM5 Gene to Introduce Mutations with the Potential to Inhibit HIV-1

C. Dufour, A. Claudel, N. Joubarne, N. Merindol, T. Maisonnet, M. B. Plourde, L. Berthoux

This study edits the human TRIM5 gene to introduce HIV-1 inhibitory mutations but finds limited restriction activity in HEK293T cells.

bioRxiv · Oct 3, 2017Microbiology

Gene knockout shows that PML (TRIM19) does not restrict the early stages of HIV-1 infection in human cell lines

N. Masroori, P. Cherry, N. Merindol, J.-x. Li, C. Dufour, L. Poulain, M. B. Plourde, L. Berthoux

This paper uses CRISPR-Cas9 to knockout PML in human cell lines and shows it does not restrict early HIV-1 infection or IFN-I-mediated inhibition.

bioRxiv · May 21, 2017Immunology