Cancer BiologybioRxivPreprint
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma
U. N. Wasko, J. Jiang, A. C. Garcia…·R. H Vonderheide
This study evaluates the therapeutic potential of RMC-7977, a broad-spectrum RAS inhibitor, in pancreatic ductal adenocarcinoma models, showing strong anti-tumor effects with minimal impact on normal tissues.