Author

K. E. Helfrich

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. B. Frias· 1 shared A. C. Poholek· 1 shared A. N. Fooks· 1 shared B. Xie· 1 shared G. J. Marrero· 1 shared I. Sipula· 1 shared L. M. D'Cruz· 1 shared L. Y. Beppu· 1 shared

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2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. B. Frias

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintDec 14, 2019

Blimp-1 in adipose resident Tregs controls adipocyte beiging and obesity

L. Y. Beppu, X. Qu, G. J. Marrero…·L. M. D'Cruz

This study shows that Blimp-1 in adipose Tregs suppresses IL-10, reducing beiging and increasing obesity risk, while its ablation improves insulin sensitivity and reduces weight in mice.

DOI 10.1101/2019.12.14.874693

mousegenetic perturbation / CRISPR

𝕏 PostBluesky