Author

K. Flatmark

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

K. G. Fleten· 2 shared A. A. Fretland· 1 shared A. B. Keeton· 1 shared A. B. Ward· 1 shared A. K. Mitra· 1 shared A. M. Yousef· 1 shared A. T. Kristensen· 1 shared B. Edwin· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

K. G. Fleten

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Author profile →

3 papers

Recent·Most cited

A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer

J. Foote, T. E. Mattox, A. B. Keeton, X. Chen, F. T. Smith, K. L. Berry, T. W. Holmes, J. Wang, C.-H. Wang, A. B. Ward, A. K. Mitra, V. R. Alcantara, C. Hardy, K. G. Fleten, K. Flatmark, , G. A. Piazza

This paper introduces ADT-007, a novel pan-RAS inhibitor that effectively blocks tumor growth in mouse models of GI cancer by targeting RAS activation and inducing apoptosis.

bioRxiv · May 17, 2023 · PreprintCancer Biology

Antitumor activity of intraperitoneal paclitaxel in orthotopic patient-derived xenograft models of mucinous appendiceal adenocarcinoma

I. Ito, P. N. Dickson, A. M. Yousef, Z. A. Naini, M. G. White, K. G. Fleten, K. Flatmark, K. F. Fournier, N. W. Fowlkes, J. P. Shen

This study evaluates the antitumor effect of intraperitoneal paclitaxel in orthotopic patient-derived xenograft models of mucinous appendiceal adenocarcinoma, showing significant tumor growth reduction.

bioRxiv · Feb 1, 2023 · PreprintCancer Biology

A microRNA Signature of Metastatic Colorectal Cancer

E. Hoye, B. Fromm, P. H. M. Bottger, D. Domanska, A. T. Kristensen, C. Lund-Andersen, T. W. Abrahamsen, A. A. Fretland, V. J. Dagenborg, S. Lorenz, B. Edwin, E. Hovig, K. Flatmark

This study identifies a microRNA signature associated with metastatic progression in colorectal cancer using NGS data from 268 samples.

bioRxiv · Jun 1, 2020 · PreprintCancer Biology