Author

K. Grzyb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Golebiewska· 2 shared A. Michelucci· 2 shared A. Muller· 2 shared A. Oudin· 2 shared A. Skupin· 2 shared B. Klink· 2 shared F. Hertel· 2 shared M. Mittelbronn· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. Golebiewska

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Author profile →

2 papers

Recent·Most cited

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

Y. A. Yabo, P. M. Moreno-Sanchez, Y. Pires-Afonso, T. Kaoma, B. Nosirov, A. Scafidi, L. Ermini, A. Lipsa, A. Oudin, D. Kyriakis, K. Grzyb, S. K. Poovathingal, A. Poli, A. Muller, R. Toth, , A. Golebiewska

This study characterizes the tumor microenvironment in glioblastoma patient-derived xenografts and patient tumors, revealing phenotypic heterogeneity in microglia and their functional adaptations.

bioRxiv · Mar 5, 2023Cancer Biology

Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine

A. Golebiewska, A.-C. Hau, A. Oudin, D. Stieber, Y. A. Yabo, V. Baus, V. Barthelemy, E. Klein, S. Bougnaud, O. Keunen, M. Wantz, A. Michelucci, V. Neirinckx, A. Muller, T. Kaoma, , S. P. Niclou

This study shows that glioma PDOX models accurately represent patient tumors and can predict treatment responses in personalized medicine.

bioRxiv · Apr 24, 2020Cancer Biology