Author

A. Lipsa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

S. P. Niclou· 3 shared A. Golebiewska· 2 shared A. Oudin· 2 shared A. Poli· 2 shared B. Nosirov· 2 shared L. Ermini· 2 shared A. Anand· 1 shared A. Cosma· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

S. P. Niclou

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

T-Cell-Mediated Killing in Glioblastoma Organoids induced by Adenoviral Delivery of the CIITA Transgene

I. Salvato, E. Klein, A. Poli, M. Rezaeipour, L. Ermini, B. Nosirov, A. Lipsa, A. Oudin, V. Baus, G. M. Dore, A. Cosma, A. Golebiewska, A. Marchini, S. P. Niclou

This study shows that adenoviral delivery of CIITA enhances T-cell mediated killing of glioblastoma organoids, with some MHC-II-independent immune responses observed.

bioRxiv · Jan 22, 2024 · PreprintCancer Biology

CDK12/CDK13 inhibition disrupts a transcriptional program critical for glioblastoma survival

S. Lier, S. O. Lund, A. Lipsa, K. B. M. Frauenknecht, I. D. Rein, P. Jain, A. Lang, E. Lang, N. Meyer, A. Datta, S. Anand, G. Nesse, R. J. Forstrom, A. Klungland, J. E. Rinholm, , D. P. Pandey

This study shows that inhibiting CDK12 and CDK13 reduces glioma cell proliferation and migration, and disrupts transcription and cell cycle progression in glioblastoma.

bioRxiv · Jul 14, 2023Cancer Biology

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

Y. A. Yabo, P. M. Moreno-Sanchez, Y. Pires-Afonso, T. Kaoma, B. Nosirov, A. Scafidi, L. Ermini, A. Lipsa, A. Oudin, D. Kyriakis, K. Grzyb, S. K. Poovathingal, A. Poli, A. Muller, R. Toth, , A. Golebiewska

This study characterizes the tumor microenvironment in glioblastoma patient-derived xenografts and patient tumors, revealing phenotypic heterogeneity in microglia and their functional adaptations.

bioRxiv · Mar 5, 2023Cancer Biology