Author

K. Hahn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:human· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

S. Rottenberg· 2 shared A. A. Lo· 1 shared A. Brown· 1 shared A. Ciccarelli· 1 shared A. Degasperi· 1 shared A. Ettinger· 1 shared A. Julien-Laferriere· 1 shared A. Letko· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

S. Rottenberg

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Charting the Heterogeneity of Colorectal Cancer Consensus Molecular Subtypes using Spatial Transcriptomics

A. Valdeolivas, B. Amberg, N. Giroud, M. Richardson, E. J. C. Galvez, S. Badillo, A. Julien-Laferriere, D. Turos, L. Voith von Voithenberg, I. Wells, A. A. Lo, E. Yangüez, M. Das Thakur, M. Bscheider, M. Sultan, , K. Hahn

This study uses spatial transcriptomics and single-cell RNA sequencing to analyze colorectal cancer subtypes, revealing intratumoral heterogeneity and cell communication events in CMS2 carcinomas.

bioRxiv · Jan 23, 2023 · PreprintCancer Biology

A living biobank of canine mammary tumor organoids as a comparative model for human breast cancer

M. Inglebert, M. Dettwiler, K. Hahn, A. Letko, C. Droegemueller, J. G. Doench, A. Brown, Y. Memari, H. Davies, A. Degasperi, S. Nik-Zainal, S. Rottenberg

This study establishes a canine mammary tumor organoid biobank to model human breast cancer, showing genetic and phenotypic conservation and utility for drug testing and CRISPR screening.

bioRxiv · Sep 2, 2022Cancer Biology

An optogenetic method for interrogating YAP1 and TAZ nuclear-cytoplasmic shuttling

A. M. Dowbaj, R. P. Jenkins, J. M. Heddleston, A. Ciccarelli, T. Fallesen, K. Hahn, M. Montagner, E. M. Sahai

This paper introduces an optogenetic method to measure nuclear-cytoplasmic shuttling rates of YAP1 and TAZ, showing phosphorylation enhances nuclear export and that import/export rates are correlated within cells.

bioRxiv · Jun 8, 2020Cell Biology

Connectivity analysis of GEF/GTPase networks in living cells

D. J. Marston, M. Vilela, J. Ren, G. Glekas, M. Azoitei, G. Danuser, J. Sondek, K. Hahn

The paper uses biosensors to analyze GEF-GTPase interactions in living cells and identifies functional relationships that regulate cell edge dynamics.

bioRxiv · Aug 8, 2019Cell Biology

Stochastic methods for inferring states of cell migration

R. J. Allen, C. Welch, N. Pankow, K. Hahn, T. C. Elston

This study develops stochastic computational tools to analyze cell migration states, revealing two distinct migration states in MEFs and HeLa cells, linked to RhoG and Rac1 activity.

bioRxiv · Jan 17, 2018Cell Biology

Local Control of Intracellular Microtubule Dynamics by End Binding Protein 1 (EB1) Photo-Dissociation

J. van Haren, A. Ettinger, H. Wang, K. Hahn, T. Wittmann

This paper demonstrates precise spatial and temporal control of microtubule dynamics using photo-dissociation of EB1, showing that neither the GTP cap nor CKAP5 can sustain polymerization at physiological rates.

bioRxiv · Jan 10, 2017Cell Biology