Cell BiologybioRxivPreprint
Collagen receptor GPVI-mediated platelet activation and pro-coagulant activity aggravates inflammation and aortic wall remodelling in abdominal aortic aneurysm
T. Feige, A. Bosbach, K. J. Krott…·M. Elvers
This study shows that GPVI-mediated platelet activation worsens AAA by promoting inflammation and aortic wall remodeling, suggesting GPVI as a therapeutic target.