M. Johansson

Dynamic binding of the bacterial chaperone Trigger factor to translating ribosomes

This study uses single-particle tracking to show that Trigger factor binds to translating ribosomes in E. coli with two distinct modes and competes with SRP for RNC binding.

Real-time single-molecule 3D tracking in E. coli based on cross-entropy minimization

This paper develops a method for sub-millisecond 3D tracking of single molecules in E. coli using cross-entropy minimization and achieves high precision with a new PSF positioning technique.

Role of the Topoisomerase IIα Chromatin Tether domain in Nucleosome Binding & Chromosome Segregation

This study shows that TopoII's Chromatin Tether domain binds methylated histone H3K27me3 to prevent anaphase ultra-fine bridges, ensuring proper chromosome segregation.

Mechanism of DNA surface exploration and operator bypassing during target search

This study uses SMCT-FCS to show LacI slides on DNA, bypassing target sequences by hopping out of the DNA groove, revealing a speed-accuracy trade-off in target search.

More than a flying syringe: Using functional traits in vector borne disease research

This paper presents a framework for incorporating vector functional trait variation into disease transmission models to better understand and predict vector-borne disease dynamics.

Inferring rates of metastatic dissemination using stochastic network models

This paper develops a stochastic network model to infer metastatic dissemination rates using clinical data from tongue and ovarian cancer, revealing site-specific dissemination rates and enabling patient-specific metastasis predictions.

Elimination of ribosome inactivating factors improves the efficiency of Bacillus subtilis and Saccharomyces cerevisiae cell-free translational systems

This study shows that disrupting genes encoding ribosome inactivating factors improves the activity of cell-free translational systems in Bacillus subtilis and Saccharomyces cerevisiae.