PhysiologybioRxiv
Enterohepatic transcription factor CREB3L3 protects atherosclerosis via SREBP competitive inhibition
H. Shimano, Y. Nakagawa, Y. Yunong Wang…·M. Araki
This study shows CREB3L3 protects against atherosclerosis by inhibiting SREBP activity through competitive antagonism, reducing lipogenic and cholesterogenic gene expression.
DOI 10.1016/j.jcmgh.2020.11.004