Author

V. Pillai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Approach:deep learning· 1

Frequent Co-Authors

A. Thomas-Tikhonenko· 3 shared K. E. Hayer· 3 shared S. Y. Yang· 3 shared Y. Barash· 3 shared A. S. Naqvi· 2 shared A. Suresh· 2 shared K. L. Black· 2 shared M. A. Kuriakose· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

A. Thomas-Tikhonenko

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Mapping the Cellular Biogeography of Human Bone Marrow Niches Using Single-Cell Transcriptomics and Proteomic Imaging

S. Bandyopadhyay, M. Duffy, K. J. Ahn, M. Pang, D. Smith, G. Duncan, J. Sussman, J. Zhang, J. Huang, Y. L. Lin, B. Xiong, T. Imtiaz, C.-h. Chen, A. Thadi, C. Chen, , K. Tan

This study maps human bone marrow niches using single-cell transcriptomics and proteomic imaging, identifying distinct cellular environments and their roles in hematopoiesis and AML.

bioRxiv · Mar 14, 2024 · PreprintCell Biology

Alternative splicing of its 5'-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

Z. Ang, L. Paruzzo, K. E. Hayer, C. Schmidt, M. Torres Diz, F. Xu, U. Zankharia, Y. Zhang, S. Soldan, S. Zheng, C. D. Falkenstein, J. P. Loftus, S. Y. Yang, M. Asnani, P. King Sainos, , A. Thomas-Tikhonenko

This study identifies alternative splicing of CD20 mRNA that generates translation-deficient isoforms, contributing to resistance to CD20-directed immunotherapies.

bioRxiv · Feb 19, 2023Immunology

Establishment and Characterization of Three Novel CAF Cell Lines from HNSCC Patients

N. Dwivedi, H. Bahar, S. D N, C. E. Cherry, C. Gangadharan, A. Suresh, M. A. Kuriakose, V. Pillai, S. P K, M. Das

This study establishes three novel CAF cell lines from HPV-negative HNSCC patients to study tumor-stroma interactions and identify new therapeutic targets.

bioRxiv · Jan 8, 2023 · PreprintCancer Biology

FBXW7β isoform drives transcriptional activation of a proinflammatory TNF cluster in normal and malignant pro-B cells

S. Y. Yang, K. E. Hayer, H. Fazelinia, M. Asnani, K. L. Black, A. S. Naqvi, V. Pillai, L. A. Spruce, Y. Barash, K. S. Elenitoba-Johnson, A. Thomas-Tikhonenko

The paper identifies FBXW7β as a predominant isoform in normal and malignant pro-B cells, showing it drives a proinflammatory TNF gene cluster.

bioRxiv · Apr 24, 2022 · PreprintCell Biology

Establishment and characterization of novel autologous pair primary cultures from two Indian non-habitual tongue carcinoma patients

N. Dwivedi, C. G, V. Pillai, M. A. Kuriakose, A. Suresh, M. Das

The paper establishes and characterizes novel autologous primary cultures from two Indian non-habitual tongue carcinoma patients to study tumor-stroma interactions.

bioRxiv · Jan 25, 2022 · PreprintCancer Biology

Aberrant splicing in B-cell acute lymphoblastic leukemia

K. L. Black, A. S. Naqvi, K. E. Hayer, S. Y. Yang, E. Gillespie, A. Bagashev, V. Pillai, S. Tasian, M. R. Gazzara, M. Carroll, D. Taylor, K. W. Lynch, Y. Barash, A. Thomas-Tikhonenko

The paper identifies widespread aberrant splicing in pediatric B-ALL, showing that splicing factor deregulation drives splicing changes and contributes to disease.

Nucleic Acids Research · Oct 24, 2018Peer-reviewedCancer Biology