E. Robinson

Identification of retinal tau oligomers, citrullinated tau, and other tau isoforms in early and advanced AD and relations to disease status

This study quantifies retinal tau isoforms in early and advanced AD and links them to brain pathology and cognitive status.

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains

The paper identifies short RNAs that prevent and reverse pathological fibrillization of RNA-binding proteins like FUS and TDP-43, showing therapeutic potential for ALS/FTD.

Make Like a Tree and Leave: How Will Tree Species Loss and Climate Change Alter Future Temperate Broadleaved Forests?

The paper models how climate change and tree disease will affect temperate broadleaved forests in Wales, predicting changes in species composition and carbon dynamics over 30 years.

M. tuberculosis microvariation is common and is associated with transmission: analysis of three years prospective universal sequencing in England

This study identifies microvariation in M. tuberculosis strains using sequencing data from England, finding that mixed infections are associated with increased tuberculosis transmission.

Evolutionary PTEN Gene Divergence Underpins the Remodeling of Plant Vacuolar Compartments

The paper shows that evolutionary divergence in PTEN genes is critical for vacuolar compartment remodeling in plants, particularly in embryonic and xylem cells.

Development of a novel rodent rapid serial visual presentation task reveals dissociable effects of stimulant vs non-stimulant treatments on attention

This study develops a novel rodent RSVP task to assess attention and tests stimulant and non-stimulant treatments, finding distinct effects on accuracy, impulsivity, and response timing.

Trans-epithelial migration is essential for neutrophil activation during RSV infection

This study shows that trans-epithelial migration is necessary for neutrophil activation during RSV infection, with three phases of neutrophil behavior identified.

Investigating the effects of incremental conditioning and supplemental dietary tryptophan on the voluntary activity and behaviour of mid-distance training sled dogs

This study examines how tryptophan supplementation and training affect sled dogs' activity and behavior, finding reduced agonistic behaviors with tryptophan but no effect on activity levels.

DNA Thermo-Protection Facilitates Whole Genome Sequencing of Mycobacteria Direct from Clinical Samples by the Nanopore Platform

This paper develops a thermo-protection buffer to enable direct whole genome sequencing of Mycobacteria from clinical samples using Nanopore technology, achieving high coverage at low bacterial concentrations.

Neutrophil: Airway Epithelial Interactions Result in Increased Epithelial Damage and Viral Clearance during RSV Infection

This study shows that neutrophils enhance RSV clearance but increase airway epithelial damage through mechanisms involving activation, degranulation, and apoptosis.

Ultrasound- and microbubble-mediated targeted delivery of therapeutic microRNA-loaded nanocarriers to deep liver and kidney tissues in pigs

This study validates a platform for ultrasound and microbubble-mediated delivery of microRNA-loaded nanocarriers to deep liver and kidney tissues in pigs, showing enhanced delivery and no tissue damage.

No evidence that portion size influences food consumption in male Sprague Dawley rats

This study finds no evidence of a portion size effect in male Sprague-Dawley rats under various experimental conditions, suggesting the human PSE may involve socio-cognitive processes.

MinION Nanopore Sequencing of Multiple Displacement Amplified Mycobacteria DNA Direct from Sputum

This study evaluates the effectiveness of multiple displacement amplification followed by MinION sequencing for detecting Mycobacteria DNA in sputum samples.

Whole genome sequencing for predicting clarithromycin resistance in Mycobacterium abscessus

This study uses whole genome sequencing to predict clarithromycin resistance in Mycobacterium abscessus by identifying known and novel resistance-determining mutations.

Automated detection of bacterial growth on 96-well plates for high-throughput drug susceptibility testing of Mycobacterium tuberculosis

This paper introduces AMyGDA, a software tool for automated detection of M. tuberculosis growth on 96-well plates to determine drug susceptibility.

Identifying mixed Mycobacterium tuberculosis infection and laboratory cross-contamination during Mycobacterial sequencing programs

The paper develops metrics to detect mixed Mycobacterium tuberculosis infections and cross-contamination in sequencing data from tuberculosis diagnostic labs.

Back-Translating A Rodent Measure Of Negative Bias Into Humans: The Impact Of Induced Anxiety And Unmedicated Mood And Anxiety Disorders

This study translates a rodent negative affective bias measure to humans, finding increased bias and reduced drift rate in those with mood/anxiety symptoms, but no effect from induced anxiety.

Amazon Mechanical Turk as a platform for borderline personality disorder research

This study tests using Amazon Mechanical Turk to research borderline personality disorder, finding it suitable for studying diverse psychopathology levels.

A quantitative evaluation of MIRU-VNTR typing against whole-genome sequencing for identifying Mycobacterium tuberculosis transmission: A prospective observational cohort study

This study evaluates MIRU-VNTR typing against whole-genome sequencing to identify Mycobacterium tuberculosis transmission, finding low predictive value of MIRU-VNTR and lineage-specific performance.

Control of artefactual variation in reported inter-sample relatedness during clinical use of a Mycobacterium tuberculosis sequencing pipeline

The paper identifies genomic regions in Mycobacterium tuberculosis that contribute to artefactual variation in bacterial similarity searches and proposes a method to reduce such variation.