Author

K. Lebrigand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 5 Research Focus:cell type annotation· 4 Assay:scRNA-seq· 4 Organism:mouse· 3 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2

Frequent Co-Authors

P. BARBRY· 4 shared V. Magnone· 4 shared G. Vassaux· 3 shared R. Rezzonico· 3 shared S. Leroy· 3 shared A. Baeri· 2 shared A. Paquet· 2 shared B. Mari· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersPathology

P. BARBRY

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Aging affects reprogramming of murine pulmonary capillary endothelial cells after lung injury

M. Truchi, M. Gautier-Isola, G. Savary, H. Cadis, C. Scribe, A. Baeri, A. Lingampally, V. Magnone, C. Girard-Riboulleau, M.-J. Arguel, C. de Schutter, J. Fassy, N. Boukrout, R. Larrue, N. Martin, , B. Mari

This study compares transcriptomic changes in pulmonary capillary endothelial cells from young and aged mice after lung injury, finding age-related differences in resolution and fibrotic signatures.

bioRxiv · Jul 11, 2023 · PreprintPathology

Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics

B. Cambien, K. Lebrigand, A. Baeri, N. Nottet, C. Compin, A. Lamit, O. Ferraris, C. Peyrefitte, V. Magnone, J. Henriques, L.-E. Zaragosi, S. Giorgetti-Peraldi, F. Bost, M. Gautier-Isola, R. Rezzonico, , G. Vassaux

This paper uses single-cell transcriptomics to identify DDIT4 as a resistance factor against oncolytic vaccinia virus in canine TNBC cells.

bioRxiv · May 29, 2020Cancer Biology

High dimensional single-cell analysis reveals iNKT cell developmental trajectories and effector fate decision

T. Baranek, K. Lebrigand, C. de Amat Herbozo, L. Gonzalez, G. Bogard, C. Dietrich, V. Magnone, C. Boisseau, Y. Jouan, F. Trottein, M. Si-Tahar, M. Leite-de-Moraes, T. Mallevaey, C. Paget

The paper uses single-cell transcriptomics to uncover developmental trajectories of iNKT cells and identifies FHL2 as a regulator of iNKT1 fate.

bioRxiv · May 12, 2020Immunology

Single-cell RNA sequencing reveals novel cell differentiation dynamics during human airway epithelium regeneration

S. Ruiz Garcia, M. Deprez, K. Lebrigand, A. Paquet, A. Cavard, M.-J. Arguel, V. Magnone, I. Caballero, S. Leroy, C. H. Marquette, B. Marcet, P. Barbry, L.-E. Zaragosi

This study uses single-cell RNA sequencing to uncover differentiation dynamics and cell trajectories in human airway epithelium regeneration, identifying novel cell subpopulations and signaling pathways involved.

bioRxiv · Oct 24, 2018Cell Biology

Targeting the DNM3OS / miR-199a~214 cluster for the treatment of fibroproliferative diseases

G. Savary, M. Buscot, E. Dewaeles, S. Diazzi, N. Nottet, E. Courcot, J. Fassy, K. Lebrigand, I. S. Henaoui, N. Martis, C. Van der Hauwaert, S. Leroy, L. Plantier, A. Paquet, C. L. Lino Cardenas, , N. Pottier

This study identifies DNM3OS as a key regulator of fibroblast activation via miRNAs, offering a therapeutic target for fibrotic diseases like IPF.

bioRxiv · Jan 4, 2018 · PreprintPathology