PhysiologybioRxivPreprint
Substrate-Specific Function of PNPLA3 Facilitates Hepatic VLDL-Triglyceride Secretion During Stimulated Lipogenesis
S. M. Johnson, H. Bao, C. McMahon…·J. Liu
This study defines the physiological role of wild-type PNPLA3 in maintaining hepatic VLDL-TG secretion and shows that the I148M variant impairs this function during lipogenic conditions.
DOI 10.1101/2023.08.30.553213